Regenerative Stem Cell Therapy
What is Cell Therapy?
Our Combined Cell Therapy procedure utilizes 3 components of regenerative medicine to help reduce pain and inflammation due to osteoarthritis, soft tissue disorders, and osteonecrosis.
Mesenchymal stem cells, derived from fat and bone marrow cells in your own body, have the potential to give rise to a variety of different cell types. They are essentially “blank” cells with the ability to form into fat cells, cartilage, bone, tendon, muscle, and skin. Mesenchymal stem cells can be found in many areas of the body, with the best sources being bone marrow and adipose (fat) tissue. Due to the plasticity of these cells, they can play a large role in regenerative repair.
For this procedure, stem cells will be extracted from your own body’s fat tissue and bone marrow and injected into the affected area of your body. Your own body’s cells have the potential to reduce pain and inflammation associated with osteoarthritis and other orthopedic conditions and regenerate cartilage, joint space, soft tissue, and bone. When injected into the affected area- whether it be the joint, muscle, cartilage, or bone- these stem cells begin to differentiate into the type of cell in that environment.
Platelet Rich Plasma
Platelets, which are found in the blood, were assumed to only play a role in the clotting cascade to prevent profuse bleeding. Recently, we have found that platelets actually play a crucial role in healing as well. Upon activation, platelets release various growth factors contained inside of them. These growth factors are responsible for the repair process and work with stem cells in your body.
The amount of blood needed to produce Platelet Rich Plasma, or PRP, depends on the joint or tendon requiring treatment and the type of system used. The process is similar to getting blood drawn for testing or for blood donation. Once it is extracted, the blood is put into a centrifuge where it is spun at very high speeds- separating the various elements of the blood.
Fat Graft/ Adipose Cells
This step involves the extraction of fatty tissue for the harvesting of stem cells. Fat compartments are a very rich source of stem cells, specifically mesenchymal stem cells which can differentiate into cartilage, bone, and ligaments. The procedure can be compared to a smaller version of liposuction, since less fat is needed for the purposes of stem cell therapy.
Stem cells are collected by aspirating bone marrow from the posterior iliac crest. The bone marrow is a central compartment in all of your bones which produces red blood cells, white blood cells, platelets, and has a large concentration of Hematopoietic stem cells. Hematopoietic stem cells are responsible for creating vessels.
You may qualify if…..
- You have an indication of Osteoarthritis from degeneration or chronic injury
- You have a tendon, muscle, ligament, or other soft tissue injury- either requiring or not requiring surgery
- You have an indication of Osteonecrosis of any major joint
- You are 18 to 90 years of age
- If female, you are not pregnant or lactating
- You do not have a history of corticosteroid use OR you have suspended corticosteroid use for 1 month prior to cell therapy
- You are able to comply with the treatment plan and periodic interviews/questionnaires
Dr. Darr is currently offering Combined Cellular Therapy study opportunities for treating Osteoarthritis, Soft Tissue injuries, and Avascular Necrosis. Combined Cellular Therapy uses adipose-derived stem cells, bone-marrow derived stem cells, and platelet-rich plasma (PRP) to concentrate mesenchymal cells and growth factors and relocates them to the damaged site. These cells come from your own body, and are minimally processed before before being injected. For more information about these studies, cost of treatments, and your eligibility, or to schedule an appointment with Dr. Darr, please call (985) 273-5888 or email (email@example.com) the Research Coordinator, Heather Jones.