Alpha-2-Macroglobulin (A2M) is a naturally occuring molecule found in your blood that acts as a powerful protector against cartilage breakdown. A2M attaches to and removes the destructive enzymes, called proteases, that damage cartilage cells and tissues in the joint space. The A2M injection is derived from your own blood and contains a concentrated dose of 6X more A2M than what already occurs in your blood naturally. The goal of this is to provide the necessary amount of A2M to bind and remove destructive proteases associated with cartilage cell and tissue breakdown within the joint space. This treatment can be helpful in patients who have not had as much success with previous cellular therapy procedures.